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olp6 cells  (BioResource International Inc)

 
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    BioResource International Inc olp6 cells
    Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using <t>OLP6</t> cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.
    Olp6 Cells, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/olp6 cells/product/BioResource International Inc
    Average 90 stars, based on 1 article reviews
    olp6 cells - by Bioz Stars, 2026-06
    90/100 stars

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    1) Product Images from "Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes"

    Article Title: Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes

    Journal: Translational Psychiatry

    doi: 10.1038/tp.2017.182

    Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using OLP6 cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.
    Figure Legend Snippet: Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using OLP6 cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.

    Techniques Used: In Vitro, In Vivo, Cell Culture, Quantitative RT-PCR, Gene Expression, Control, Expressing, Injection, MANN-WHITNEY



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    olp6 cells  (BioResource International Inc)
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    BioResource International Inc olp6 cells
    Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using <t>OLP6</t> cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.
    Olp6 Cells, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/olp6 cells/product/BioResource International Inc
    Average 90 stars, based on 1 article reviews
    olp6 cells - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

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    Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using OLP6 cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.

    Journal: Translational Psychiatry

    Article Title: Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes

    doi: 10.1038/tp.2017.182

    Figure Lengend Snippet: Effects of ligands for nuclear receptors in vitro and in vivo . ( a ) Top row: schematic of the experiment using OLP6 cells. During the first 4 days, the cells were cultured in an undifferentiated condition. During the subsequent 4 days, the cells were cultured in a differentiated condition. On day 7, each ligand was added. On day 8, the transcript levels were measured by quantitative RT-PCR. Bottom row: quantitative RT-PCR analysis of oligodendrocyte-related genes in OLP6 cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate. This examination was performed in triplicate. ( b ) Top row: schematic of the experiment using KATO-III cells. Bottom row: gene expression of CCK and CALB2 in KATO-III cells treated with 0.1, 0.3 or 1 μ m bexarotene or 5, 15 or 50 μ m bezafibrate and analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh / GAPDH was used as an internal control. P -values were calculated using Dunnett’s test for multiple comparisons (compared with DMSO). This examination was performed in triplicate. ( c ) Top row: experimental design for the administration of bexarotene. Mice received daily injections from 6 to 9 weeks of age (vehicle or bexarotene, 30 or 100 mg kg −1 , once per day). Bottom row: gene expression of Olig2 and Apc in mouse prefrontal cortexes (PFCs) analyzed by quantitative RT-PCR. Values are means±s.e. Gapdh was used as an internal control. P -values were calculated using Dunnett's test for multiple comparisons (compared with vehicle). Note that 30 mg kg −1 bexarotene administration elicited a significant increase in the expression of Olig2 and Apc . ( d , e ) Locomotor responses to injection of MK-801 (0.3 mg kg −1 ) in the vehicle- and bexarotene (30 mg kg −1 )-pretreated mouse groups. For both groups, the last treatment was administered 180 min before MK-801 injection. Values are means±s.e. P -values were calculated using two-way repeated measures ANOVA followed by post hoc Mann–Whitney U test d . P -values were calculated using unpaired t- tests e . # P <0.1, * P <0.05, ** P <0.01, *** P <0.001, **** P <0.0001.

    Article Snippet: OLP6 cells (RIKEN BioResource Center Cell Bank, Tsukuba, Japan) were incubated in a humidified atmosphere with 5% CO 2 at 33 °C in the proliferative stage.

    Techniques: In Vitro, In Vivo, Cell Culture, Quantitative RT-PCR, Gene Expression, Control, Expressing, Injection, MANN-WHITNEY